Conference Paper
Population genomics in Astyanax
Herman, A., Weagley, J., Jeffery, W.R., Borowsky, R., Brandvain, Y., Bilandžija, H., Espinasa, L., O'Quin, K., Ornelas-García, C., Gilbertson, E., Passow, C., Yoshizawa, M., Warren, W. and McGaugh, S.E.
Record Number:
3254
Year:
2017
Journal:
AIM 2017
Abstract:
The genetic underpinnings of many cave-associated traits are different among cave populations
even within the new and old lineages, and we are examining divergent outlier loci between cave
and surface fish within caves among these lineages to infer commonalities about the evolutionary
process across multiple origins of the cave phenotype. To address these goals, we generated whole
genome resequencing data from three cave populations and two surface populations, including
surface and cavefish populations from both the new and old lineages. We also sequenced a closely
related congener A. aeneus to serve as outgroups for polarizing changes in the A. mexicanus
cavefish. In total, we have 45 resequenced genomes (7.3x-19x per individual aligned to the
reference genome), and have thoroughly explored the relationships between populations, revealing
extensive gene flow between new and old cavefish lineages, while the surface fish lineages remain
distinct. This gene flow shapes how we interpret adaptation to the cave environment, and the
interpretation of outlier loci, and will provide fruitful avenues for future research into gene-flow
mediated adaptation.
Times Cited:
1
Relevent Species: