Journal Article
Of cancer and cave fish
Gatenby, R.A., Gillies, R.J. and Brown, J.S.
Record Number:
3742
Year:
2011
Journal:
Nature Reviews Cancer
Pages:
237-238
Volume:
11
Abstract:
We propose that the drivers of carcinogenesis lie more in the adaptive changes that are enabled by local or systemic alterations of tissue architecture than in the genetic changes observed in cancer cells. A full understanding of cancer biology and therapy through a cataloguing of the cancer genome is unlikely unless it is integrated into an evolutionary and ecological context.
Times Cited:
1
Relevent Species: